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EGCG
Product Number :
HL1010
Product Name :
EGCG
CAS No. :
989-51-5
Synonyms :
(-)-Epigallocatechin Gallate;Epigallocatechol Gallate
Chemical Name :
Molecular Formula :
C22H18O11
Molecular Weight :
458.37
Molecular Structure :
Appearance :
Off-white to pink powder
Specification :
98+%
Application :
Registration :
Storage Condition :

Biological Activityβ-secretase (BACE1) inhibitor (IC50 = 1.6 μM); inhibits amyloid assembly. Inhibits the formation of amyloid fibrils by proteins such as Aβα-synuclein and huntingtin. Reduces Aβ42-induced cell death in three different cell types. Also inhibits glutamate dehydrogenase. Inhibits cell growth and selectively induces apoptosis in A431 and human pancreatic cancer cells. Also a DNMT1 inhibitor.


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