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Fidaxomicin(Lipiarmycin)

  Catalogue No. : C13670
  Product Name: Fidaxomicin(Lipiarmycin)
  Synonym: R-Tiacumicin B; Tiacumicin B; OPT-80; PAR-101;Clostomicin B1;Dificid
  Chemical Name: 3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-b-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-b-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one
  CAS No. : 873857-62-6
  Structure :
  Molecular Formula: C52H74Cl2O18
  Molecular Weight: 1058.04
  Appearance: White solid
  Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
  Purity: >99%
  Usage: Fidaxomicin is a recently approved antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.
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