Product Number :	CL1287
Product Name :	Cobimetinib (GDC-0973)
CAS No. :	934660-93-2
Synonyms :	Cobimetinib; GDC-0973; XL518
Chemical Name :	(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone
Molecular Formula :	C21H21F3IN3O2
Molecular Weight :	531.31
Molecular Structure :
Appearance :	White or off-white powder
Specification :	98+%
Application :
Registration :
Storage Condition :

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.

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