| Product Number : |
CL1632 |
| Product Name : |
Afatinib |
| CAS No. : |
850140-72-6 |
| Synonyms : |
BIBW2992 |
| Chemical Name : |
|
| Molecular Formula : |
C24H25ClFN5O3 |
| Molecular Weight : |
485.94 |
| Molecular Structure : |
 |
| Appearance : |
White solid powder |
| Specification : |
98+% |
| Application : |
|
| Registration : |
|
| Storage Condition : |
Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.
Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.
