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Afatinib
Product Number :
CL1632
Product Name :
Afatinib
CAS No. :
850140-72-6
Synonyms :
BIBW2992
Chemical Name :
Molecular Formula :
C24H25ClFN5O3
Molecular Weight :
485.94
Molecular Structure :
Appearance :
White solid powder
Specification :
98+%
Application :
Registration :
Storage Condition :

Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.

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