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DMXAA
Product Number :
CL1889
Product Name :
DMXAA
CAS No. :
117570-53-3
Synonyms :
(ASA-404; Vadimezan;NSC 640488); 5,6-Dimethylxantheonone-4-acetic acid
Chemical Name :
Molecular Formula :
C17H14O4
Molecular Weight :
282.29
Molecular Structure :
Appearance :
Light brown powder
Specification :
98+%
Application :
Registration :
Storage Condition :

Vadimezan, also known as DMXAA and ASA404, is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide, resulting in hemorrhagic necrosis and a decrease in angiogenesis. This agent also stimulates the anti-tumor activity of tumor-associated macrophages.


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