Escitalopram Oxalate (Cipralex; Lexapro; Lu10171; Lu-10171; Citalopram;Cytalopram), the oxalate salt of Escitalopram which is an approved antidepressant drug, is a potent and selective serotonin (5-HT) reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram Oxalate is the citalopram S-(+)-enantiomer. It has the ability to block [3H]-5-HT uptake and [125I]-RTI-55 binding in COS-1 cells that express the 5-HTT human serotonin transporter, with Ki values of 3.9±2.2nM and 6.6±1.4nM, respectively.
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