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GNE-9815
Product Number :
CL2830
Product Name :
GNE-9815
CAS No. :
2729996-45-4
Synonyms :
Chemical Name :
Molecular Formula :
C26H22FN5O2
Molecular Weight :
455.48
Molecular Structure :
Appearance :
Off-white to light yellow powder
Specification :
98+%
Application :
Registration :
Storage Condition :

GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers

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->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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