| Product Number : |
CL1542 |
| Product Name : |
LDN-193189 |
| CAS No. : |
1062368-24-4 |
| Synonyms : |
LDN193189;DM-3189 |
| Chemical Name : |
|
| Molecular Formula : |
C25H22N6 |
| Molecular Weight : |
406.48 |
| Molecular Structure : |
 |
| Appearance : |
Light yellow to yellow powder |
| Specification : |
98+% |
| Application : |
|
| Registration : |
|
| Storage Condition : |
LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.
