Product Number :	CL1320
Product Name :	LY294002
CAS No. :	154447-36-6
Synonyms :	NSC 697286; SF 1101
Chemical Name :
Molecular Formula :	C19H17NO3
Molecular Weight :	307.34
Molecular Structure :
Appearance :	White to yellow powder
Specification :	98+%
Application :
Registration :
Storage Condition :

LY294002, a morpholine-containing compound designed based on the flavonoid quercetin, is a potent and cell-permeable PI3K inhibitor, inhibiting PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM in cell-free assays, respectively. Additionally, it inhibits BET (for example, BRD2, BRD3, and BRD4). It is more stable in solutions than the PI3K inhibitor Wortmannin. By acting on the ATP binding site of the catalytic subunit of PI3K, LY294002 is selective against p110α, p110β, p110γ and p110δ.

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