Product Number :	CL1077
Product Name :	PD0325901 (Mirdametinib)
CAS No. :	391210-10-9
Synonyms :	PD0325901(Mirdametinib)
Chemical Name :
Molecular Formula :	C16H14F3IN2O4
Molecular Weight :	482.19
Molecular Structure :
Appearance :	White powder
Specification :	99+%
Application :
Registration :
Storage Condition :

Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.

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