Product Number :	CL2376
Product Name :	Pirfenidone(AMR69)
CAS No. :	53179-13-8
Synonyms :	AMR69
Chemical Name :
Molecular Formula :	C12H11NO
Molecular Weight :	197.33
Molecular Structure :
Appearance :	White to light yellow powder
Specification :	98+%
Application :
Registration :
Storage Condition :

Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.

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