Product Number :	CL2193
Product Name :	Pravastatin Sodium
CAS No. :	81131-70-6
Synonyms :	CS-514 sodium
Chemical Name :
Molecular Formula :	C23H35NaO7
Molecular Weight :	446.51
Molecular Structure :
Appearance :	Off-white to Pale purple powder
Specification :	98+%
Application :
Registration :
Storage Condition :

Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

 Pravastatin Sodium is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.

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