| Product Number : |
CL1853 |
| Product Name : |
Adezmapimod |
| CAS No. : |
152121-47-6 |
| Synonyms : |
SB 203580; RWJ 64809;PB 203580 |
| Chemical Name : |
|
| Molecular Formula : |
C21H16FN3OS |
| Molecular Weight : |
377.43 |
| Molecular Structure : |
 |
| Appearance : |
White to light yellow powder |
| Specification : |
98+% |
| Application : |
|
| Registration : |
|
| Storage Condition : |
Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.
Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.
