| Product Number : |
CL1076A |
| Product Name : |
Sorafenib Tosylate |
| CAS No. : |
475207-59-1 |
| Synonyms : |
|
| Chemical Name : |
|
| Molecular Formula : |
C28H24ClF3N4O6S |
| Molecular Weight : |
637.03 |
| Molecular Structure : |
 |
| Appearance : |
White to off-white powder |
| Specification : |
99+% |
| Application : |
|
| Registration : |
|
| Storage Condition : |
Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.
