Product Number :	CL2658
Product Name :	Tesirine(SG3249)
CAS No. :	1595275-62-9
Synonyms :	SG3249
Chemical Name :
Molecular Formula :	C75H101N9O23
Molecular Weight :	1496.65
Molecular Structure :
Appearance :	White to light yellow powder
Specification :	95+%
Application :
Registration :
Storage Condition :

Tesirine (SG-3249; SG3249), cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer used as an antibody-drug conjugate (ADC) payload; Tesirine was designed to combine the potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. Rovalpituzumab tesirine is a first-in-class ADC directed against delta-like protein 3 (DLL3), a novel target identified in tumour-initiating cells and expressed in small-cell lung cancer.

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